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Luven ICO



Luven ICO



Your chance to be a part of the ONGOING PROJECT in the REAL sector of economy that promotes a unique cancer diagnostic technology designed 
to save millions of lives.




Let’s do it together!




Regardless of the rapid development of modern medicine and biology cancer takes annually millions of human lives. One cancer patient, worldwide, dies from this disease every 30 seconds. Everyone in this world has friends or relatives who have died from or have been diagnosed with cancer. Malignant tumors relate to the most pressing issues of modern medicine. 

They take 2nd place to heart diseases by frequency and occurrence in the general structure of morbidity, disability and mortality. According to the WHO, around 10 mln people worldwide are annually diagnosed with cancer. The key to successful cancer treatment is early diagnosis. If detected at the early stage, when there are no visible symptoms, cancer can be cured without any complex aggressive therapies.


The limited ability to accurately localize cancer in the human body is also a significant problem. The main task is not only to detect a disease, but also to specify the affected organ. As of today, we have developed a unique unrivaled diagnostic method with substantial advantages over existing practices.




Our mission is to save 1,000,000 lives annually




Millions of people can save their lives if they get early diagnosis of possible health problems. Most malignant tumors detected early can be successfully cured!




According to the World Health Organization 

  • Each year 8,000,000 people die from cancer;
  • Every day 27,000 patients are diagnosed with cancer and this number is constantly growing;
  • Due to the late diagnosis more than half of cancer patients die, because manifestations of the disease appear in advanced stages;
  • In the last 10 year the number of oncology patients has increased by around 25%;



Each year around 200,000 children, worldwide, develop cancer, 100,000 of which die, mostly because of late diagnosis.
Stage 1 and even stage 2 cancer responds well to treatment.


The average 5-year survival rate of cancer 
patients after treatment

  • Treatment in stage 1 cancer – around 93% of patients survive;
  • Treatment in stage 2 cancer – around 75% of patients survive;
  • Treatment in stage 3 cancer – around 55% of patients survive;
  • Treatment in stage 4 cancer – around 13% of patients survive;

The Luven technology allows to detect the disease in its early stages, thus, preventing its progression in thousands of patients.


Scientific foundation of the method


Any process in the body reflects in the cell, a structural unit of the body. Buccal cells (cells from the inside of the cheek) are the fastest to respond to any changes.

We have established some regularities in the changes in electrical activity of buccal cells and their cytomorphological parameters in case of any changes in the life processes.

By examining various parameters of cells and their combinations, our system called The Luven Diagnostic allows, with a high degree of accuracy, to detect oncological diseases, localization of a diseased organ, tendency of progression of the disease and comorbidities.

A large number of studies ,conducted in cancer centers ,showed that The Luven methods’ accuracy is up to 96% for some types of cancer, which is a very high rate comparable to biopsy


HOW THE TEST WORKS

Diagnostic procedure


  • A patient card should be filled out in the computer program;
  • A buccal swab is carefully collected with a mouth spatula and placed under the microscope;
  • The program records a video from the microscope and transfers it to the processing center;
  • Within several minutes the program receives a printable report; Based on data processing results the report shows:
  • Cancer lesions in the body, if any;
  • Predisposition or liability to cancer;
  • Comorbidities according to the international classification of diseases (ICD-10 and TNM);





Patents



We already have patents in Ukraine and Russia, also we've submitted an application to WIPO that secures our international reputation and allows us to obtain local patents in various counries.

The technology for diagnosing cancer is protected by the official publication of WIPO (World Intellectual Property Organization) - WO2016089336 The use of technology without author's permission is prohibited








Our history

The development of this method started in early 1983 at the research institute, chair for genetics. Based on the cellular theory by Rudolf Vichow, a team of scientists was working on a diagnostic method and studying buccal cells.

It took 28 years to collect a so-called “deviation album” which established a relationship between cell parameters and body conditions.



Ms. Galina Shchukina, a genetic scientist and cytologist, was at the head of the scientific research. She conducted an in-depth study of scientific papers describing a new biophysical concept of the gene activity regulation based on the role of relationship between homologous chromosomes and genome. Ms. Galina then requested her husband Mr. Alexander Shchukin to search for a technique allowing to accurately count a number of positively and negatively charged nuclei. 

Since then Mr. Alexander, a nuclear physicist who studied at the chair for experimental nuclear physics, became a part of the team and buckled down to that difficult task. During eight years the lab scientists were trying to find an accurate method to count charged nuclei and get a precise number. As a result of thousands of experiments, they invented an ion trap sending impulses on cells and, thus, allowing to differentiate between positively and negatively charged cell nuclei. In this manner, 8 years later, it became possible to calculate the percentage of negative charged nuclei (bioelectrical charge) and to easily estimate an actual physiological age of any organism

It was the first milestone in the development of LUVEN a unique diagnostic and treatment system.

The Shchukiny family took the lead of the team of scientists continuing further studies and research of this concept. All of this culminated in 2004 when they developed a new diagnostic method the main idea of which is that any changes in the body manifest at the cellular level, including buccal cells.

It has been more than 30 years now since they started comparing changes in healthy and diseased cells and studying interrelation between them. So far, has collected samples for examination from more than twenty thousand patients.

From 2007 until the present day, a new cancer diagnostic method has been formalized and automated by the scientists in cooperation with Mr. Nikolay Shchukin, Ms. Galina and Mr. Alexander’s son and postgraduate student of chair for biochemical engineering.
In 2010 the team embraced IT specialists and mathematicians who put all the knowledge and formulae into the software of Luven Diagnostic system. They set up a commercial enterprise promoting the new technology.

In 2014 they launched Luven Diagnostic franchise which boosted development in many countries (more than 23 newly opened diagnostic rooms diagnosed more than two thousand patients), but soon afterwards our team faced a large number of problems that couldn’t be solved without big financial investment:

1. The software, at that time, transmitted images from the microscope to our processing center where a team of cytologists would specify parameters for the received material, after which the computer would process the data and give a result. We were putting great efforts into teaching cytologists how to correctly record image parameters which closed the door to our prospective growth. Also, our lab assistants couldn’t work 24/7 which caused long delays in text interpretations, just as the number of those tests was constantly increasing;

2. We couldn’t sell our diagnostic system to other countries, since the method required certification and clinical trials which, in turn, requires big money.

Finally, we decided to take a pause and improve the software by adding computer-assisted learning (automatic corrections of coefficients in formulae for the database of clinically confirmed patient diagnoses) that will allow us to constantly improve diagnostic accuracy, run clinical tests and re-start our project in many countries at the same time.



Why do we need ICO?


We need money for :

*further studies, since the technology allows to not only diagnose cancer, but also detect other diseases;


*debugging software for computer-assisted learning, automatic recognition of images transmitted from lab microscopes, generation of the database of patients and their test results for trending and informing patients on the necessity of being diagnosed;


*other business-related operations;

*marketing and advertising;

*opening a center in Austria to study the method;

*legal services;

*opening new labs worldwide;

*developing a diagnostic device specially for family use.




WHAT ARE BENEFITS FOR INVESTORS ?



Investment prospects

Unlike the majority of projects involving crowdfunding, our company has already completed 90% of the project.

We have already conducted studies, developed the entire procedure and received several patents for the procedure. Also, we have all the necessary equipment and software which can produce income and treat people even today.

Token holders have two opportunities :

*receiving a part of the company income;

*exchanging their tokens for testing services with a 30% discount, using or selling them to wholesale customers (such as clinics, insurance companies, physicians in private practice etc.);

*Investors from the countries where tokens equal securities (such as USA or China) will not be able to share the company income, however, they will have a possibility to exchange their tokens for tests with a 80% discount, use them or sell them to wholesale customers. It means that the company will exchange tokens for tests 5 times cheaper than the market price.

Your investment is not only a cure for a huge number of people, but also your tool for making money from the capitalization growth and test sale.



Business Model

The company will start selling sets of necessary equipment to labs, hospitals and physicians in private practice.

Tests will be read on the company servers, each test will be paid for. The diagnosis price will vary from country to country. The lowest price will be based on the current GDP per capita. The company services will cost 50% of the retail price. In this manner, we will ensure a balance between affordability of the diagnosis for the population and Company income.



Our sales target

At the preICO stage - 3 000 000 tokens 

(1st day bonus – 30%, 1st week bonus – 25%, 2nd week bonus – 20%, 3d week bonus – 15%)

At the ICO stage - 27 000 000 (1st week – 10%, 1 to 1 onwards)

9,000,000 tokens will be kept by the founders and developers of Luven Diagnostic.

Bonuses will be also awarded for the investment volume

>= 5,000 ETH 5%
>= 3,000 ETH 4%
>= 1,000 ETH 3%
>= 100 ETH 2%
>= 3 ETH 1%

Token standard: ERC20.
Rate: 1$ = 1 LVN
Participation in ICO is possible both with Ethereum and Bitcoin.


40% CLINICAL TRIALS

25% MARKETING

15% SOFTWARE

10% LEGAL PART

7% TEAM REMUNERATION

3% BOUNTY CAMPAIGN

preICO
Start: 12.12.2017 12:00 GMT
Completion: 29.12.2017 12:00 GMT

ICO
Start: 15.01.2018 12:00 GMT
Completion: 28.02.2018 12:00 GMT

If all the tokens are sold out at the PREICO stage, ICO will start earlier.

Join Our Community
















BCT Profil Link : https://bitcointalk.org/index.php?action=profile;u=1349169
ETH : 0x8630585BF2C519b74551c1eCBE50f20698Ab2049



















CIBUS WORLD

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GET FREE 2 CBT

FOOD ECOSYSTEM ON BLOCKCHAIN



CIBUS IS POISED TO CREATE FRESH REVOLUTION WITH BLOCKCHAIN 

ENABLED FOOD ECOSYSTEM 2.0 FOR 21ST CENTURY


CIBUS is bringing Trust back into Food and Dietary Supplements segments with a new decentralized, blockchain based platform. CIBUS will help its users to track and transact food and dietary supplement products to ensure highest quality,trust, transparency, reliability, efficiency, security and full traceability, at lower cost. CIBUS will create end to end B2C & B2B ecosystem that will transform how we handle and consume food in future.



CIBUS BUSINESS MODULES



Provides blockchain based food tracing 

and transparency tool to consumers.




Incentivized social networking platform that 

aims to create a global collaboration on food.


Facilitates wholesale & business to business 
trade in food & supplements.

Facilitates direct retail trade in food & supplements 
between consumers & food producers.


CIBUS AD provides an inbuilt analytics platform, 

provides rich and relevant data about user traffic

Affiliate marketing platform for 
CIBUS Retail and CIBUS Trade at competitive rates.


Standard five stage escrow services provided 

for a fee based on the transaction value.


CIBUS may consider at a later date

to open it’s own Logistics center like Fullfilment




BENEFITS TO SELLERS

  • Fast and detailed customer feedback
  • Marketing & promotion directly to consumers
  • Full control on Brands image
  • Lower cost to reach customers
  • Interoperability of scalable data

BENEFITS TO BUYERS
  • Transparency in food & dietary supplements
  • Food ecosystem on trusted blockchain
  • Higher quality at cheaper price
  • Engagement with sellers directly
  • Rewards for social proofs




  • B2B and B2C Ecosystem on Food & Dietary Supplements
  • CIBUS offers traceability and transparency over Blockchain
  • Trustless trading between Buyers and Sellers, cutting middleman
  • Various smart contracts to facilitate cross-border trade
  • CIBUS token facilitates trade, escrow, fees & loyalty rewards
  • Interoperability of data between participants within Ecosystem
  • Trust, performance & scalability at lower cost in Food business


SCAN

Buyers will scan CIBUS TRACE QR Code on the packages of food & supplements with their mobile phones to check its traceability info

ENGAGE

Consumers will participate in CIBUS SOCIAL platform with product reviews, their experience, share recipes and engage with Sellers directly

TRADE

Buyers and Sellers will execute trade via CIBUS RETAIL and CIBUS TRADE in a trusted manner using Ethereum smart contracts



BRAND LOYALTY

Growing brand lovers with engagement, transparency, confidence and satisfaction enabled by CIBUS Ecosystem

GOOD FOOD

Soon, there will be two kinds of food – cheap food and good food. CIBUS will be the key change agent enabling delivery of good food to this world

VALUE

CIBUS with trusted blockchain will unlock new value drivers using authenticity and reputation in Food trade driving profitability at lower cost



WHAT PROBLEMS DO CIBUS SOLVE ?



LACK OF TRUST

Trust deficit due to product recalls with scare of food poisoning, pathogenic microbial, pesticides & chemical contamination


LACK OF TRACEABILITY

No authentic traceability info flow through the system leaving increased room for counterfeit products, misleading labels & false claims


EASY TO MANIPULATE

Lack of consistency of origin and quality related product data leaves wide scope for product adulteration and falsifying records


HIGH COST

Rising food prices with middle men taking higher cuts, and broken systems creating inefficiencies drives cost upwards


LACK OF ENGAGEMENT

Lack of engagement between producers and consumers due to layers of middlemen filters and construes messages


NO SOCIAL PROOF

Clear lack of voice of consumers (VOC), grievance redressal and feedback loop drives poor purchase decisions


FRAGMENTED ECOSYSTEM

Broken supply chain makes it impossible for interoperability and scalability of traceability data sharing between participants


HIGH FRICTION

Inconsistent regulatory watch and inefficient quality systems implementation creates friction, confusion and increases waste









BRAND AMBASSADOR CIBUS




CIBUS PARTNER




Our Community















ETT : 0x8630585BF2C519b74551c1eCBE50f20698Ab2049

S P 8 D E


S P 8 D E 

THE GAME OF CHANCE CHANGED 

A DECENTRALIZED PLATFORM FOR GAMING DAPPS



Introduction


Spade – implemented within a protocol created and maintained by the scientists at IOHK, the pioneers in the realm of blockchain innovation and cryptography development, has its aim to revolutionize the ever-growing gaming industry as we know it today. Spade’s aim is to disrupt the multi-billion-dollar gambling industry for the first time since the creation of the Internet. The online i-gaming is the industry with no future: centralized and obscure, the online casinos currently in existence can only offer ridiculous house edges,

uncertainty in processing the payments, inward and otherwise, and the need to rely on the randomness generated elsewhere. In layman terms, you can’t be sure that the game design is fair, that the randomness used to generate game outcomes is unbiased and that you will get you money back if you win. The blockchain is the fit-for-purpose technology that is set to solve all of these issues. However, there is always a catch… In spite of all the benefits the blockchain environment introduces to the gambling world its current state of implementation can be best described by a single word – tragic. 

Blockchain based gambling platforms are plagued with issues primarily inherent to the current state of the underlying technology. Decentralization imposes heavy tax on the efficiency: games are fair, but you can’t play them. The obstacle seems unsurpassable: so should we just pause for a while and wait for the technology to advance further? No. If no one has done it before, we will. Spade is a blockchain-based platform for developing distributed gaming applications. As a platform for gaming applications with some self-respect, we are equipped with the protocol for generating fresh unbiased randomness. 

As a team with some aspirations we have it provably fair and completely decentralized. We feel that it is important to be true to the spirit of the venture we embark upon: if blockchain is the universal and undisputed source of truth then it should also be the broadcast channel for randomness. We think that single points of failure should be perceived by anyone as just a funny relic of the past. And yes, we are Proof-Of-Stake (POS) efficient in terms of cost and time alike. Spade is built on top of Ouroboros, the most advanced POS protocol that underpins the Cardano blockchain. A cradle of academic approach to the blockchain technology, Cardano is the beam of progress that shines forward towards the future of distributed applications.


The Industry 


In the European Union the online gambling industry grew nearly 19% from the first half of 2015 until the first half of 2016. The casino industry in particular generated over US$2 billion in revenues during this period. It is expected that until 2020 this number will reach US$2.25 billion per year representing about 12.5% revenue growth. 

In the US for the period 2015 until 2016 online casino revenues increased by 24.4% and are expected to reach US$4 billion by 2020. The EU and the US are just a small part of the worldwide casino industry.


Globally, the projections of the online casino show that for the period 2017-2025 the market will experience a spectacular growth of about 130% reaching the phenomenal US$97 billion with cumulative annual growth rate of nearly 11%. Currently over 6 million adults are officially participating in gambling activities around the world with projections of reaching 10 million by 2020. 

We further believe that as blockchain technologies advance, and propagate for the first time in history unbiased provable randomness, these figures will become a gross underestimation of what reality proves to be. By removing a variety of frictions from the gaming market, Spade is set to unleash the monetary gains hidden therein. We won’t take a cut from it. We are determined to create a frictionless market for gaming ideas: what previously was left to casinos and other intermediaries, now will be channeled to the community.


The Competitors 

There are many and varied casino or gambling blockchain projects, however, in our opinion only a handful deserve the attention of the public and even fewer have come anywhere close to addressing the three fundamental problems we have spoken of earlier. In short, it suffices to say that, unlike Spade none of them, have meticulously and rigorously proven to have a complete and working solution to all of three central problems. For those interested in the details, the full whitepaper presents a more in-depth analysis of the projects. Here, we think, it will suffice to just place the following table.


The table above highlights that now as never one needs to appreciate the wisdom embedded in a “devil’s in the detail” idiom: multimillion dollar casino projects who claim to revolutionize the multibillion dollar gambling industry do not appear to address the most fundamental problems this revolution creates. Everyone is recommended to briefly look at the history of the last century to see what a disaster any unplanned revolution is.

The Mechanics of Spade 

We build Spade on top of the blockchain called Cardano [25]. The Cardano project itself is a monumental work that embraced the best practices and most far reaching innovations in the area of cryptocurrencies and packed them into a single state-of-art system. In what follows we will illustrate how Spade provides an environment for the design of gambling applications which are characterized with :

1. Close-to-absent transaction fees and Proof-of-Stake powered scalability that is beyond the reach of any other on-chain casino protocol currently in existence; 

2. A mechanism to generate decentralized provably uniform randomness at arbitrary time-spans;

3. Provides rich Smart Contract functionality that allows for creativity in game design that is bounded solely by the fantasy of the developer (and the demand for the resulting product, of course);

As we have mentioned multiple times before, fairness of the outcome is essential for gambling, it is the core. Spade utilizes Cardano to design its ecosystem and thereby solves the problems normally associated with the on-chain casinos described above. 

1. Transaction fees and scalability: Ouroboros is a Proof-of-Stake protocol, meaning that at any given time, a trusted set of nodes maintain the integrity of the system. This protocol was shown in an experimental setting to be resistant to a handful of attacks that are known to plague other systems and are directly relevant to gambling protocols. 

2. Random number generation: finally, and, arguably, most importantly, Ouroboros, the POS protocol underlying Cardano blockchain in its workings fully relies upon generating unbiased (i.e. uniformly distributed) entropy. 
The beauty of the idea is that the blockchain itself serves as a broadcast channel: the uniform randomness is generated on-chain! In layman terms, this means that Ouroboros: 

a. Generates provably random numbers; 
b. Guarantees that everyone will get them. Unchanged. 

We will touch upon the topic of randomness again in the technical part below. Apart from providing elegant solutions to the existential problems of on-chain casino protocols, Cardano is a fit-for-purpose for solving several less critical issues:

3. Flexible and finance application-tailored scripting language: Cardano is designed by the masters of code and is set to follow best practices; its scripting language is tailored for financial applications: security and execution can be “extremely well understood”. Any language suited for finance is the natural candidate for casino development: the underlying logic (at least from the programming viewpoint) of these two domains is similar.

We have just now praised Cardano: it is scalable, secure, complex and yet elegant. The major takeaway, however, is that designing a successful POS protocol requires solving the same problems that constrain the creation of provably fair on-chain casinos. With Cardano as a backbone, Spade is set to become the best of its kind, this fit was just meant to be. The token distribution begins on Friday, December 08, 2017 and ends on Monday, February 12, 2018 and is scheduled. 

The Pre-Sale lasts for 14 days while each Sale phase will be seven days followed by a Jackpot that is distributed entirely within a single day after every Sale. During the Jackpots additional tokens given away to the participants of every Sale (including the Pre-Sale) – the distribution of the tokens is based on randomly generated factors with different weight (see the full white paper for details). 

In short, the earlier one buys tokens the more tokens will be allocated to them – for example, if you bought during the Pre-Sale you will receive more tokens during Jackpots I, II, III, and IV; while if you bought during Sale III then you will receive tokens only from Jackpots III and IV. Also, the earlier you bought the more “weight” (or chance for taking larger part of the Jackpots) your tokens will have during the Jackpot phases.




The token distribution begins on Friday, December 08, 2017 and ends on Monday, February 12, 2018 and is scheduled. The Pre-Sale lasts for 14 days while each Sale phase will be seven days followed by a Jackpot that is distributed entirely within a single day after every Sale. During the Jackpots additional tokens given away to the participants of every Sale (including the Pre-Sale) – the distribution of the tokens is based on randomly generated factors with different weight (see the full white paper for details). 

In short, the earlier one buys tokens the more tokens will be allocated to them – for example, if you bought during the Pre-Sale you will receive more tokens during Jackpots I, II, III, and IV; while if you bought during Sale III then you will receive tokens only from Jackpots III and IV. Also, the earlier you bought the more “weight” (or chance for taking larger part of the Jackpots) your tokens will have during the Jackpot phases.



Token Utilization




In total we will distribute 8,888,888,888 SPX tokens of which 20% (1,777,777,777.6 SPX) will remain with the team while all others will be sold. In the chart above we demonstrate how we plan to use the proceeds from the sales of the SPX token; those that remain with the team can be used for further development or urgent business requirements (e.g. advisory or operations). There is no limit on how much tokens an individual can purchase and in case some tokens are not bought during the Sale phases they will be distributed according to the following schedule:








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